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The importance of being CG-rich and the curious case of Sox2 Transcription factors involved in adult neurogenesis are single-exon genes, for example, Sox2 , Sox4 , and Sox11 , or two-exon genes, for example, Ngn2 , NeuroD1, and NeuroD2 , that are embedded in long stretches of high CG densities (CpG islands)

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